Dr. Mike Dentinger
Post-Doc
Office: ISIS 2.05 Telp: +33 368 855 217 FAX: Email: mike.dentinger@etu.unistra.fr
Education |
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2013 – 2015 |
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Master of Sciences (MS) – Chemistry-Biology 13.074/20 University of Strasbourg – Strasbourg, FRANCE 2nd year (2014-2015): 1st Semester : 12.857 Admitted(1st session) 2nd Semester : 14.035 Admitted (1st session) 1st year (2013-2014): 1st Semester : 12.567 Admitted(1st session) 2nd Semester : 12.838 Admitted (1st session)
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2013
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Licence (3rd year University degree) in Chemistry 11.459/20 University of Strasbourg – Strasbourg, FRANCE 3rd year (2012-2013): 1st Semester : 10.927 Admitted(1st session) 2nd Semester : 12.508 Admitted (1st session) 2nd year (2011-2012): 1st Semester : 12.238 Admitted (2nd session) 2nd Semester : 10.978 Admitted(1st session) 1st year (2010-2011): 1st Semester : 10.985 Admitted(1st session) 2nd Semester : 11.025 Admitted (1st session) 1st year (2009-2010): 1st Semester : 8.307 Adjourned (2nd session) 2nd Semester : 7.985 Adjourned (2nd session)
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2009 |
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Baccalauréat Général (French High school diploma) Lycée Louis Pasteur – Strasbourg, FRANCE |
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Scientific Skills
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Work Experience in Chemistry
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November 2015 - Actually
January 2015- June 2015 |
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PhD Laboratoire de Chimie et de Biomatériaux Supramoléculaires under the supervision of Prof. Luisa De Cola - University of Strasbourg - FRANCE Breakable nanocapsules for the in-vitro and in-vivo delivery of biomolecules
Master 2 internship Laboratoire de Chimie et de Biomatériaux Supramoléculaires under the supervision of Prof. Luisa De Cola and Dr. Ingrid Cabrera-Puig - University of Strasbourg - FRANCE Influence of the functionalization in the physicochemical properties and in vitro behavior of breakable mesoporous silica nanoparticles. |
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March 2014 – June 2014 |
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Master 1 internship Laboratoire de Chimie et de Biomatériaux Supramoléculaires under the supervision of Prof. Luisa De Cola and Dr. Laura Maggini - University of Strasbourg - FRANCE Synthesis of bioconjugated nanozeolites to develop a new cancer therapy in association with the Hospital of Strasbourg. |
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July 2013 – September 2013 |
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Volontary internship Laboratoire de conceptions et d’analyses de molecules bioactives with Dr. Alexandre Specht Synthesis of two-photon uncaging systems |
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Presentations and Awards
· Flash and poster presentation at the European Winter School on Physical Organic Chemistry 2016 (1st Prize Poster Award) Miscellaneous· Speaking language: French, English, Spanish (basis) · Driving license since September 5th 2010 · Activity: Basket-Ball, Movies, Football… |
A big challenge in medicine is to be able to create efficient carriers to deliver drugs and/or nucleic acids and to destroy or excreted them from the body. In particular for cancer therapy, also the targeting is still a dream. We developed stimulus responsive porous nanoparticles that can deliver drugs and breaks in small pieces after cell internalization.
Recently, a new generation of organo-hydrid mesoporous silica nanoparticles (NPs) containing redox responsive disulfide (S-S) bridges (ss-NPs) have been developed in our group. We now show how we can functionalize with targeting ligands the surface to have a better penetration for cancer cells without preventing the breakability properties of the material.